Periprosthetic Joint Infection: The Economic Impact of Methicillin Resistant Infections

A worrisome rise in the incidence of prosthetic joint infections (PJI) caused by virulent, antibiotic-resistant organisms has been noted over the past decade. In addition to higher failure rates, management of PJI caused by resistant organism is believed to be associated with a prolonged hospital stay, and need for multiple surgeries. The purpose of this multi-institutional, case-control study was to evaluate the economic impact of antibiotic resistance through studying the cost of treating PJI caused by resistant versus sensitive organisms.