Acta Orthopaedica, 87:5, 439-443, DOI: 10.3109/17453674.2016.1151292

Psychiatric disease as a risk factor in fast-track hip and knee replacement – An overview of the literature

Silas Hinsch Gylvin, Christoffer Calov Jørgensen, Anders Fink-Jensen & Henrik Kehlet
Hip Knee

Recent studies suggest that patients with psychiatric disorders tend to do worse than patients without a psychiatric diagnosis when undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA). Whether this is due to their psychiatric condition, pharmacological treatment, a combination of the two, or something else has not been thoroughly analyzed—and there are no internationally accepted guidelines for perioperative management of psychiatric patients. This overview summarizes our current knowledge on perioperative risks in patients with preoperative psychiatric disorders and the possible role of psychotropic drugs in the perioperative course. This will be useful when planning future strategies for improvement of surgical outcome following hip and knee arthroplasty.


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