Is there any superiority in the clinical outcome of mobile-bearing knee prosthesis designs compared to fixed-bearing total knee prosthesis designs in the treatment of osteoarthritis of the knee joint?

To substantiate the validity and relevance of the mobile-bearing knee prosthesis design compared to the fixed-bearing design, concerning the clinical outcome, this review was conducted. Articles published in 6 major orthopaedic journals were screened. Only randomized controlled trials, which investigate the clinical outcome, were included. The clinical outcome parameters of each study were analysed. Despite the numerous quantities of publications in orthopaedic literature, we could conclude, that only a few of them are randomized controlled trials. Although better kinematics of mobile-bearing knee prosthesis designs compared to fixed-bearing knee prosthesis designs are reported, no superiority of one of the bearing designs concerning clinical outcome could be revealed. Because no superiority of one of the designs concerning revision rate, survival and outcome can be found, the cheaper one should be the one to be recommended. For this reason, we advise that further research, comparing the costs and cost-benefit of mobile-bearing compared to fixed-bearing knee prosthesis designs, should be performed.