The Knee, ISSN: 1873-5800, Vol: 20, Issue: 6, Page: 437-41

Diabetes does not influence the early outcome of total knee replacement: A prospective study assessing the Oxford knee score, short form 12, and patient satisfaction

N. D. Clement; D. MacDonald; R. Burnett; S. J. Breusch


There is conflicting evidence as to whether diabetes mellitus influences the functional outcome and patient satisfaction after a total knee replacement (TKR). The aim of this study was to assess the effect of diabetes upon the Oxford knee score (OKS), short form (SF)-12, and patient satisfaction after TKR.


Prospective pre- and post-operative (one year) OKS and SF-12 scores for 2389 patients undergoing primary TKR were compiled, of which 275 (12%) patients suffered with diabetes. Patient satisfaction was assessed at one year.


Patients with diabetes were more likely to have a greater level of comorbidity (p < 0.001), and a worse pre-operative OKS and SF-12 score (p < 0.02), compared to those patients without diabetes. Diabetes was not a significant (p > 0.41) independent predictor of post-operative OKS or the SF-12 physical score on multivariable analysis. Although, factors more prevalent within the diabetic cohort (heart disease, vascular disease, liver disease, anaemia, depression, back pain, worse pre-operative OKS and SF-12 score) were found to be independent predictors of post-operative OKS and SF-12 physical score. Interestingly, diabetes was associated with a significantly greater improvement in mental wellbeing (SF-12 mental component), which was confirmed on multivariable analysis. Patient satisfaction was not influenced by a concomitant diagnosis of diabetes (p = 0.57).


The outcome of TKR as assessed by the OKS, SF-12, and overall patient satisfaction rates are not influenced by diabetes per se, although factors more prevalent within this population result in a worse post-operative outcome.
Level of evidence: prospective cohort study, level III.

Download article